PSYC 362 Lecture Notes - Lecture 16: Superior Temporal Sulcus, Fusiform Face Area, Prefrontal Cortex
14 Aug 2016
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Specific features of autism include: inability to develop normal social relations with others, an inability to communicate. Literal interpretation of speech: impaired imaginative ability, stereotyped movements. The first year: abnormal development of babbling, failure to play reciprocal games, hypoactive, tuned out. Preschool years: abnormal development of speech, failure to develop social skills, stereotyped behavior. Adolescence: generally see a progression in these symptoms. Adulthood: continued aloof-autistics, active, but odd, passive and friendly. Heritability of autism: mz twins exhibit a 70% concordance rate for autism, while that of dz twins is comparable to that of normal siblings (5%), 2-3% of the siblings of autistic children are themselves autistic. Co-morbidity with other disorders: chromosome x. Autism is associated with neurological disorders: phenylketonuria (pku) lack of enzyme converting phenylalanine into tyrosine interferes with myelinization of axons after birth, tourette"s syndrome. Drugs such as thalidomide (exposure during prenatal days 20-24 impairs development of the brain stem).
