BIOL 311 Lecture Notes - Lecture 24: Tumor Suppressor Gene, Cyclin-Dependent Kinase, Maturation Promoting Factor
19 Dec 2016
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La min - phos phoryla tion trigge rs nucle a r dis s olution. Ne w nucle a r e nve lope doe s n"t come from pre -e xis ting it origina te s from the er. Mp f dis cove ry (a ka cyclin b-cdk1) 1. firs t dis cove re d in frogs e ggs (africa n cla we d toa d e ggs , x. la e vis ) Re s e a rche r s toppe d the e gg in me ta pha s e of me ios is ii. Took cytopla s m, inje cte d it into e ggs a rre s te d in g2. Dis cove re d ma tura tion promoting fa ctors mp f . Took mitotic ce ll a nd ce ll in g1. Re a lize tha t s ome thing in the mitotic ce ll induce d mitotic a ctivity from g1 ce ll.
