BIOL 311 Lecture Notes - Lecture 11: I-Cell Disease, Hexa, Alglucosidase Alfa
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Begin exam iii material: history, biochemistry, microscopy, christian de duve. 1955 centrifuges (used to purify organelles) respiratory activity mitochondria. When he looked at the other pellet that was (cid:498)injured: what he did was left one pellet intact and what happen was that it responded with he also noticed respiratory activity. Hydrolytic enzymes: > 40 types: protease, nuclease, glycosidase, phosphatase. Lysosomes: single membrane bound: marker enzyme is acid phosphatase. Functions of lysosomes: heterophagy, autophagy, specialized, heterophagy a). Virchow (1860s): looked at wbc and saw a cluster os something inside. He assumed it was a rbc, and that the. Metchnikoff: hypothesized that wbc are made to fight infection. He stated that wbcs are actually engulfing what. Virchow thought to be a rbc: most people assumed wbc actually spread infections. Neuromuscular disease that also causes droopy eyelids. As a result, patients became much more sensitive to curare compare to people without mg. Patients could improve symptoms with drugs that block ache (ex. neostigmine).
