BIOL 4350 Lecture Notes - Lecture 21: Cell Membrane, Oxidoreductase, Conformational Change
22 Mar 2017
School
Department
Course
Professor
Document Summary
Ppt 14 (8-15) ppt 15 (11-13: succinyl coa is more oxidized the alpha ketoglutarate, got nadh and colinkage to coa. Electron carriers: nad+ accepts a hydride (2e+proton, only thing nad+ will accept, typically involved in oxidative reactions like going from alcohol to keto group, fad, can accept 1 electron at a time, enzymatically a different model. Just losing electrons and going to a double bonded molecule, you use fad. Enzyme regulation: most regulate enzyme, pyruvate dehydrogenase, acetyl-coa only has 2 options (citric acid cycle or build lipids, regulated by phosphorylation inactive form is phosphorylated and active form is not phosphorylated. Hub of metabolism: many of the intermediates can be used biosynthetic precursors, pyrimidine, single ringed bases in dna (cg) Citric acid cycle goes on in matrix of mitochondrion: cytosol of mitochondrion. Etc happens in the intermitochondrial membrane of mitochondria is equivalent to plasma membrane of. Complexes pump protons and proton gradient is what fuels atp synthesis.
