CHE 4341 Lecture Notes - Lecture 9: Chymotrypsin, Conformational Change, Elastase
Document Summary
Eduard buchner observes that yeast extracts can ferment sugar to. History: alcohol enzyme = in yeast in greek. Diamond to graphite [ g(25 c) = -2. 88 kj mol-1] * kinetics vs. thermodynamics the reason why diamond doesn"t suddenly convert to graphite . Ea = energy needed to reach & overcome a high energy transition state (ts) if a rxn occurs or not is a thermodynamic property determined by g. How fast a rxn occurs is a kinetic property determined by ea low ea more molecules can achieve that energy = a faster rxn rate. A catalyst = chemical that speeds up rate of a rxn without itself being consumed in process. Enzymes = proteins that serve as biological catalysts increase rate of biochemical rxn"s by (2 ways: decreasing g of the transition state (decreasing ea, providing alternate route w/a lower energy ts (decreasing ea) 2 components to a chemical rxn: kinetic/rate, thermodynamic/energy.
