PSYC BC 1119y Lecture Notes - Lecture 6: Reuptake, Myelin, Axoplasmic Transport

• School: Barnard College
• Department: Psychology
• Course: PSYC BC 1119y
• Professor: Russell Romeo

Document Summary

Ligand: substance that acts on (binds to) a receptor (activates or blocks it) Agonist: substance that binds to a receptor and initiates/activates a response like a neurotransmitter (ntx)- acts like a neurotransmitter- can produce epsps or ipsps. Antagonist: substance that binds to a receptor and blocks it and prevents action of neurotransmitter- won"t get either. Fast (ionotropic ligand-gated ion channel: neurotransmitter binds directly to a receptor in channel, channel is activated+opens immediately, ions flow across membrane for brief time. Dendrites twisted around the muscle fibers open na+ channels in the sensory neuron. Cell fires ap, jumps along from node to node, gets to spinal cord. Synapses into a motor neuron of the spinal cord. Cell opens na+ channels, through epsp summation leads to depolarization, leads to ap in motor neuron. Ap goes down to muscle fiber, synapses on muscle cell, muscle flexes, causes knee to jerk. Tests muscle tone, how fast you send signals (testing myelin)