PR 680 Lecture Notes - Lecture 5: Nazi Human Experimentation, Syphilis, Terminal Illness

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Populations in research requiring additional considerations and protections. The national bioethics advisory committee defines vulnerable subjects as people who have difficult providing voluntary, informed consent arising from limitations in decision-making capacity or situational circumstances or because they are especially at risk for exploitation. Many of the regulations and discussions in bioethics that surround protecting human subjects in research came from (now classified) unethical research practices. These people are now referred to as vulnerable populations that need extra consideration or protection. U. s. public health service tuskegee study of untreated syphilis in the negro male . In these cases, the research subject were incapable of protecting their own interests. Contributions to their vulnerability include a lack of ongoing informed consent process and allowed these things to occur. It is important to include vulnerable populations because their vulnerability is what researchers are trying to understand more, devising ways to make it less severe, accommodate, reduce, focus efforts on, or prevent completely.

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