PHYS 215 Lecture 9: Lecture 9 - PHYS 215

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What causes the rise of the action potential: an increase in p-na. How does the increase in p-na occur: opening of the outer gate of the voltage-operated na+ channel (voc-na, sodium channels" activation gate. What are the 2 gates of the voltage-operated/sensitive na channel: outer gate (activation gate, opens and closes fast. Inner gate is closing or closed: what is the purpose of the refractory period, permits the ap to move in one direction, allows the neuron to recover from the ap. What causes the ap: neuron undergoes a small depolarization to threshold (-70 mv to -60 mv, voc-na channels open due to opening of the fast-outer gate (activation gate) What causes the ap to stop: decrease of the voc-na channel (closing of the slow inner gate or inactivation gate) and increase in p-k due to opening of the voc-k channel (opening of the one slow gate)

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