NATS 1670 Lecture Notes - Lecture 39: Clonal Selection, Complement System, Antigen
Document Summary
Neutralization: ab neutralizes toxins, binds to attachment molecules. As dr. ridgeon says in george bernard shaw"s play the doctor"s dilemma, osponin is. Occurs an antibody bound to pathogens what you butter the disease germs with to make your white blood corpuscles eat them. To recognize a trillion of possible antigens, individually and specifically. Each lymphocyte has a specific antibody that is expressed for its lifetime. In order to mount an effective response we need to have sufficient cells specific for the antigen in question (at least a million cells) It is not possible having 1 million x i trillion (10^15) cells in the body just for specific immunological response. The immune system has an extremely low frequency of cells specific for each trillion of specificities. (5-10/cell) When a cell encounters its specific ag, it replicates extensively, turning ~5-10 cells into millions of progeny.