KINE 3020 Lecture Notes - Lecture 7: Dystonia, Substantia Nigra, Pars Reticulata

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Basal ganglia a group of subcortical nuclei: 5 structures. Cortical info striatum output areas. Direct path for motor cortex activation: striatum (caudate & putamen; input, sustained action / initiation of action. No inhibition of ventrolateral thalamus become active: motor cortex activation. Indirect path for motor cortex inhibition: inhibition of unwanted movements. Basal ganglia = context encoder: selectively activates & inhibits movements. Programming the self-initiated movements (from the memory) Planning & control of complex movements (organizes smooth) The actual plan is from premotor area (motor plan menu) Basal ganglia chooses the right one based on the context: among all the valid options (from pm) choose the best action energy saving, inhibits unwanted movements and releases this inhibition to trigger movement. Stops / inhibits all the possible actions first. And then chooses the right one (removes inhibition for this one) Controlled action requires both go and stop signals: bg provides both go and stop signals.

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