KINE 1020 Lecture Notes - Lecture 10: Sarcopenia
Document Summary
The decline is chronic/persistent and may lead to restrictions in movements. Rate and magnitude of changes are modifiable but the effect isn"t reversible. Maintaining/improving muscular strength reduces limitations by over in both genders. Decreasing skeletal muscle mass and strength w/ aging: Loss of hormonal adaptions, neurological influences and programmed cell death (aka sarcopenia) pathways. Sarcopenia associated with apoptosis is characterized by dna breaking up/dna fragmentation and. Sacropenia: loss of muscle mass and strength due to aging. Reduced aif, improved mitochondrial function, dereased levels of apoptosome, improved calcium handling.