KINE 1020 Lecture Notes - Lecture 24: Membrane Potential, Neuromuscular Junction, T-Tubule
29 Mar 2016
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Document Summary
Many sites have been identified in the fatigue process central-to-peripheral* A regulatory mechanism in the brain selects an optimal pace" that will preserve homeostasis by continuously adjusting intensity during exercise. By doing so, the cg serves to protect the body from metabolic inefficiency by reducing motor recruitment and keeping a metabolic reserve. Impact on neuromuscular junction (nmj: neuromuscular junction: failure at the nmj may be attributable to; Muscle fibre membrane might develop a higher threshold for stimulation, No biochemical evidence that nmj blockage is a problem. or uptake of acetylcholine) The quality of the action potentials (electrical signals) are changed. Fatigue at the sarcolemma site is associated with a change in membrane potential; Resting membrane electrical potential is becoming more positive (~+10mv) ; with exercise (increased excitability) altered ion movements (leaky membrane) An accumulation of k+ would eventually lead to deactivation. the threshold for excitation and.
