EECS 1022 Lecture Notes - Lecture 7: Channel Types, Charybdotoxin, Tetraethylammonium

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Nmsa receptors at the post-synaptic membrane: in conclusion: plasticity = nmda receptors are stable in number and. Ampa/glur receptors are variable: discuss the diversity of k+ channels. K channels are more diverse than any other channel. The diversity is in both structure and function and it allows for specificity in organs, cells and tissues. K+ channel subunits may be composed of either 2, 4 or 6 tm -helices . Evolution has allowed each cell type to select for specific k channel blends to meet its needs and functions. This diversity is possible through replication, mrna splicing of channel gene transcripts, mutations and other post translational modifications. 5. 1) briefly discuss what features are held in common that allow us to group k+ channels together. This sequence is important because it forms the h5 selectivity pore. The pore region of all channels is surrounded by 2 segments.

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