CHEM 3050 Lecture Notes - Lecture 51: Binding Domain, Cell Membrane, Symporter
3 May 2018
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CHEM 3050
Lecture 51
o ABC transporters
▪ ATP Binding cassette (ABC)
▪ Use ATP energy to pass material into the cell,
it transports material against its gradient
▪ Solute binding protein binds solute; complex
binds transporter
▪ Binding domain is stimulated to bind and
hydrolyze ATP
• Phosphate is not transferred to enzyme
▪ This opens channel for solute to pass through
Secondary Active Transport
- Symporter (type of transporter) can move glucose
into cell with Na ions
- Na ion gradient is already established by Na/K –
ATPase
- Glucose can then exit the cell as internal [glucose]
increases.
Membrane Fusion
- Important in many cellular processes
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