CHEM 3050 Lecture Notes - Lecture 45: Fluid Mosaic Model, Lipid-Anchored Protein, Membrane Protein
3 May 2018
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CHEM 3050
Lecture 45
Lipid-Linked Proteins
- Soluble in proteins except for lipid anchor
- Some of them have transmembrane regions
Fluid Mosaic Model
- Membrane proteins float randomly in sea of lipids
- Movement restricted by
o Interactions with other proteins and cytoskeletal
proteins
- Membrane protein may
o Be immobile attached to cytoskeleton
o Mobile within small area freely mobie
- Proteins as well as lipids may be asymmetrical in
membrane
Principles of Membrane transport
- Movement of ions result in membrane potential
o Concentration of Na inside is less than the
concentration of Na outside ([Na+]in < [Na+]out )
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