BIOL 2905 Lecture Notes - Lecture 15: Nuclear Pore, Moodle, Peptide

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December 2, 2015- last class *screencasts up on moodle. Pro are things like bacteria; have dna(not nucleus) but not organelles. Mrna has to come out of a nuclear pore -> all in textbook in super detail. Mrna binds to a ribosome in cytoplasm-> making a new polypeptide -> translation. Transcripton and tranlations in prokaryotes happen at same time. Ribosome binds to mrna and goes along 5"-3" direction. First seqauence called signal sequence of amino acids. Big protein rna particle called signal recognition particles (bunch of proteins and rna) that will recognize that signal sequence. Translation stopped and direct the whole complex to the er. Stops translation ; brings the complex to the er-> spr receptors. Translation then resumes in the er ; the polypeptide is stuffed into the er lumen(space) and/or membrane => called translational translocation. Sumanas site has video describing this -> translation linked . Mrna in ek has a 5 methyl cap in and 3" polya tail.

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