CH202 Lecture 13: Ch202 lecture 13
Document Summary
Extremely fast absorption time (less than 5 sec to brain) Risk of cancers from tars/hydrocarbons if smoked. Transdermal: absorbs across skin (often slowly but stably) Intranasal: absorbs across mucous membranes (rapidly) (aka insufflation ) (many blood vessels in nose) Potentially serious damage to skin or mucous membranes (deviated septum/hole when snorting cocaine) Effective for delivering medication across the highly vascularized membranes of the large intestine; good for outpatients who can"t swallow or are vomiting. On the importance of understanding the essentials of the nervous system. Specific parts of the brain specific apects of behaviour. Key principles: the part of the brain that has greater than normal metabolic activity will dominate the behavioral output of the organism (a typical assumption in fmri studies) Action potentials propagate forwards down the axon and into the synaptic terminals - Presynaptic terminals where the drug have the effects. Drug (molecular) structure often mimics the (molecular) structure an endogenous neurotransmitter.
