BI236 Lecture Notes - Lecture 5: Triglyceride, Chromosome, Dna Replication
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Multiple choice.
1.Origins of replication...
A. occur at many sites on bacterial and human chromosomes
B. contain one replication fork each where the daughter stands are being sythesized
C. initiate replication in a uni-directional manner
D. result in bubbles opened by helicases
E. occur at one site per chromosome
2.Telomerase...
A. is important for the replication of circular chromosomes | |||||||||||||||||||||||||||||||||||||||||
B. is important for the replication of linear chromosomes | |||||||||||||||||||||||||||||||||||||||||
C. carries a template in the form of a DNA molecule | |||||||||||||||||||||||||||||||||||||||||
D. sythesizes RNA primers | |||||||||||||||||||||||||||||||||||||||||
E. both the 1st and 2nd option are correct 3.What are topoisomerases?
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1. | In addition to identifying the genetic material, the experiments of Avery, MacLeod, and McCarty with different strains of Streptococcus pneumoniae demonstrated that | ||||||||||
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2. | In order to show that DNA in cell extracts is responsible for genetic transformation in Streptococcus pneumoniae, important corroborating evidence should indicate that _______ also destroy transforming activity. | ||||||||||
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3. | Based on what you have learned about the experiments conducted by Griffith and Avery and colleagues with bacteria, which of the following would result in transformation of living R cells? | ||||||||||
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4. | A-T base pairs in a DNA double helix | ||||||||||
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5. | If 23 percent of the bases in a sample of double-stranded DNA are adenine, what percentage of the bases are uracil? | ||||||||||
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6. | The uniform diameter of the DNA structure provides evidence for | ||||||||||
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7. | If a sequence of one strand of DNA is 5â²-TGACTATC-3â², what is the complementary strand? | ||||||||||
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8. | What structural aspect of the DNA facilitates dissociation of the two DNA strands for replication? | ||||||||||
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9. | If the MeselsonâStahl density gradient experiment had resulted in two bands of DNA molecules after only one round of replication, one containing only 15N and the second only 14N, this result would have indicated that replication was | ||||||||||
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10. | The nucleoside analogue acyclovir, which is used to treat herpes simplex virus (HSV) infections, lacks a 3â² hydroxyl group (âOH). Predict what will happen if the host cell DNA polymerase incorporates a molecule of acyclovir into an elongating strand of HSV DNA. | ||||||||||
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11. | Which of the following does not demonstrate the stability of the DNA double helix? | ||||||||||
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12. | What effect would a primase inhibitor have on DNA replication? | ||||||||||
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13. | To replicate their DNA in a timely manner, most eukaryotic chromosomes | ||||||||||
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14. | Which statement about DNA replication is false? | ||||||||||
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15. | In many eukaryotes, there are repetitive sequences called telomeres at the ends of chromosomes. After successive rounds of DNA replication, the _______ strand becomes shorter. In some cells, an enzyme called _______ repairs the shortened strand. | ||||||||||
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16. | A researcher studies normal human fibroblast cells. They can be maintained in culture but die off after about 30 cell generations. Unexpectedly, a colony of cells continues to survive and divide past 30 generations. Which scenario is most likely true for these cells? | ||||||||||
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17. | If DNA polymerase III introduces an incorrect nucleotide, what is the first corrective action made by the DNA repair system? | ||||||||||
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18. | Choose the correct order of the following four events in the excision repair of DNA: (1) Base-paired DNA is made complementary to the template. (2) Damaged bases are recognized. (3) DNA ligase seals the new strand to existing DNA. (4) Part of a single strand is excised. | ||||||||||
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19. | Six complete cycles of PCR should result in a _______-fold increase in the amount of DNA. | ||||||||||
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20. | When double-stranded DNA is heated to temperatures above 90°C, it denatures. Denaturation is a process that | ||||||||||
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Which of the following is NOT a direct consequence of the fact that DNA polymerase can only build onto the end of an existing nucleic acid?
Question 6 options:
DNA replication requires primers | |
Bits of DNA are lost from the ends of your chromosomes in each successive round of replication | |
RNA is involved in DNA replication | |
The enzyme "primase" is needed for DNA replication | |
There are multiple origins of replication on each eukaryotic chromosome |
How does a nucleotide sequence code for a protein in nearly all living organisms?
Question 7 options:
a sequence of 3 nucleotides can code for one of 64 different amino acids | |
a sequence of 2 nucleotides can code for one of 64 different amino acids | |
a sequence of 2 nucleotides can code for one of 20 different amino acids | |
a sequence of 3 nucleotides can code for one of 20 different amino acids | |
a sequence of 3 nucleotides can code for 3 different amino acids |
Fill in the blanks. To make one strand of DNA, _________ monomers are linked together in a chain, forming a polymer we call a(n) ________ .
Question 8 options:
nitrogenous bases, hydrogen bond | |
nucleotide, nucleic acid | |
amino acid, nucleic acid | |
nucleotide, nitrogenous base | |
amino acid, protein |
Which of the following was NOT part of the ideas that Darwin used in his book On the Origin of Species?
Question 9 options:
organisms vary in characteristics that affect survival and reproduction | |
variation in traits is often heritable | |
descent with modification explains life's unity and life's diversity | |
organisms inherit characteristics from their parents that the parents acquired in their own lifetimes | |
natural selection is a cause of adaptive evolution |
Here is a hypothetical mRNA sequence:
5' G G A U G C U A G U A U G A 3'
What is the amino acid sequence encoded by this mRNA?
Question 10 options:
Met-Ile-Val | |
Asp-Ala-Ser-Met | |
Met-Leu-Val | |
Ser-Met-Ile-Val | |
Gly-Cys |