Psychology 2220A/B Lecture Notes - Lecture 6: Opioid Use Disorder, Anterior Pituitary, Posterior Pituitary

• School: Western University
• Department: Psychology
• Course: Psychology 2220A/B
• Professor: Jody Culham

Document Summary

Liga(cid:374)d = (cid:862)ke(cid:455) that fits i(cid:374) the lo(cid:272)k(cid:863) Mechanism for epigenetics (changes to dna expression: electrical synapses (not chemical like ionotropic/metabotropic) action potential can directly jump across synapse without chemical transmission, seen where signals need to be fast (ex. Types of synapses: axons can interact with dendrites (most common, axons and cell body of another neuron, axon and axon, dendrite and dendrite. Drugs can act at any stage of synaptic transmission. Agonists: drugs that increase the effectiveness of synaptic transmission. An endogenous ligand usually activates its cognate receptor and is therefore classified as an agonist. Exogenous ligand (drug/toxin) resembles the endogenous ligand + capable of binding to the receptor and activating it = receptor agonist. Antagonists: drugs that decrease the effectiveness of synaptic transmission. Some substances (cid:271)i(cid:374)d to re(cid:272)eptors (cid:271)ut do(cid:374)(cid:859)t a(cid:272)ti(cid:448)ate them (just block agonist from binding to receptors = competitive antagonist)