Physiology 3120 Lecture Notes - Lecture 3: Zona Pellucida, Inner Cell Mass, Human Chorionic Gonadotropin

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Gamete transport getting together with estrogen: as sperm moves along the female tract, their # drops dramatically, takes ~20 min to get to the ampulla, sperm can sense temperature & chemicals (sp. Progesterone: during ovulation, body temp + p increases and sperm can sense this, by day 7 post-fertilization, the egg will reach implantation. Getting there the guys story: an average human ejaculate contains over one hundred million sperm, but only a few dozen (0. 002%) complete the journey. Capacitation: capacitation is final sperm education, completed in the female reproductive tract, alters, sperm motility (hyperactivity, sperm plasma membrane (prep for fusing; i. e. cholesterol removal, less cholesterol in the membrane makes it easier to fuse. Fertilization: meiosis ii completed, two pronuclei fuse. Start to fuse from envelop disintegration: zygote is created, rapid mitosis begins. ** polar bodies are stuck there until hatching occurs. Formation of the zygote and 2 cell stage within 24 hours the fertilization process happens in about 24 hours.

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