Pharmacology 2060A/B Lecture Notes - Lecture 14: Resting Potential, Neuropharmacology, Methyl Group

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Neuropharmacology is the study of how drugs affect the function of the central nervous system. There are many disorders of the central nervous system and most of them have a component that is mediated by a biochemical imbalance. In neuropharmacology we attempt to treat this biochemical imbalance with drugs. Unfortunately the drugs treat the symptoms of disease but not the cause. The brain is composed of literally millions of neurons. Neurons are cells in the brain that act to process and transmit signals and information. Neurons are excitable cells that transmit information by electrical and chemical signaling. The start of information transfer begins at the dendrite, which receives a signal from another neuron. This causes action potentials (electrical signaling) to propagate along the axon of the neuron. When the action potential reaches the pre-synaptic nerve terminal, it causes release of neurotransmitters (chemical signaling) which pass the signal along to the next neuron, via a synapse (see below)

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