Pathology 2420A Lecture Notes - Lecture 6: Oncotic Pressure, Extracellular Fluid, Fluid Compartments

• School: Western University
• Department: Pathology
• Course: Pathology 2420A
• Professor: Candace Gibson

Document Summary

Infarction - the formation of an infarct; a localized area of ischemic necrosis produced by occlusion of the arterial supply or the venous drainage of the part. Intracellular - fluid found within cells; intracellular fluid (icf). These molecules include the plasma proteins; albumin is responsible for most of the osmotic pressure since it is the most. Normal fluid control mechanism depends on: starling"s law, local factors, lymphatic obstruction, vascular permeability, systemic factors, cardiovascular function, overall fluid balance, salt retention. Starling"s law: definition: movement of fluid between vessels and tissue is governed by the balance between 4 forces (figure 1). Edema will occur when there is: an increase in intravascular hydrostatic pressure. Clinical examples: congestive heart failure: right side failure peripheral edema or left side failure lung edema, deep venous thrombosis of lower legs, a fall in colloid osmotic pressure/oncotic pressure of plasma: due to hypoproteinemia.