Pathology 3240A Lecture Notes - Lecture 8: Vascular Endothelial Growth Factor, Leukocyte Adhesion Deficiency, Starling Equation
28 Sep 2017
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Document Summary
Causes of disease: pathology = study of disease and the changes in cells, tissues, and organs, pathologists clinical and experimental, techniques, gross examination, light microscopy, electron microscopy = subcellular structures, molecular pathology = genes. Immunohistochemistry = antigens: disease occurs when cells fail to adapt or adaptation becomes harmful, most diseases are multifactorial (genetic and environmental factors, physical signs = objective observed, ex. Fever: clinical symptoms = subjective reported by patient, ex. Post-operative infection: prognosis = anticipated course of disease & expected final outcome, epidemiology = study of disease in populations, health indicators: life expectancy, infant mortality, prevalence = total number of cases. Epidemiology of cancer in canada: older canadians most affected, most common = prostate & breast cancer, lung, colon, top mortality = lung, prostate, breast, colon, lifetime probability of dying from cancer: women = 24%, men = 29% Idiopathic = of unknown etiology: disease is caused by disturbance to cells, genetic insults = single mutations, chromosomal alterations.
