Microbiology and Immunology 3820A Lecture Notes - Lecture 6: Molecular Mimicry, Immunoglobulin G, Systemic Lupus Erythematosus
7 Nov 2017
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Document Summary
Allergy: allergy is the production of ige antibodies in response to a protein allergen, condition is called atopy allergic reaction, atopic individual, a. k. a. Ingested materials: our body should not respond in allergic reaction. Allergic reaction: the most common symptoms: people with one atopic condition are more likely to develop another atopic condition, can occur singularly or in combination. Effector th cell subsets: we have different subsets of t helper cells. Ige will enter back into circulation and back into inflamed tissue and bind to mast cells. 4: pollen binds pollen-specific ige abs (important, binding activates the mast cell, secrete cytokines, pro-inflammatory cytokines & chemokines, degranulate, releases histamine into the tissue, occurs within minutes. Asthma: allergen enters lower respiratory tract, smooth muscle contraction- tight chest. Rhinitis vs. asthma: theory- allergen type, dose and exposure time are likely responsible for type of response, 70% of people who get asthma have some sort of allergy within the family.
