Microbiology and Immunology 2500A/B Lecture Notes - Lecture 2: Genitourinary System, Adaptive System, Microorganism
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Innate immunity is the first line of defense against a pathogen. It is constantly ready to destroy a pathogen effective at stopping majority of pathogens at early stage. Fight it off so (cid:395)ui(cid:272)kl(cid:455) that (cid:455)ou do(cid:374)"t e(cid:448)e(cid:374) k(cid:374)o(cid:449) (cid:455)ou (cid:449)e(cid:396)e i(cid:374)fe(cid:272)ted. Innate immune defenses: barriers, block pathogen entry into tissues. Innate cells and proteins: rapidly eliminate pathogens that enter tissues. If innate immunity is unsuccessful: certain innate cells initiate adaptive immunity to help eliminate the pathogen. I(cid:374)(cid:374)ate i(cid:373)(cid:373)u(cid:374)e s(cid:455)ste(cid:373) does(cid:374)"t stop (cid:271)ut (cid:449)o(cid:396)ks alo(cid:374)g adapti(cid:448)e system to fight. 40,000 microorganisms you inhale with every breath do(cid:374)"t (cid:374)eed to k(cid:374)o(cid:449) time takes up to 2 weeks for adaptive to come along and help innate. Share the same innate immunity conserved through evolution: we share with plants and invertebrates, adaptive system is unique to vertebrates. Responds immediately to a pathogen: pathogen is usually eliminated before symptoms arise. Same immune response to identical pathogen with each exposure.