Biology 1201A Lecture Notes - Lecture 9: Kinetochore, Prometaphase, Microtubule
Document Summary
We continue our exploration the origins of genetic diversity. Outcomes: meiosis 4 unique haploid and mitosis 2 identical diploid. Prophase of meiosis: pairing of homologous chromosomes (tetrads) Meiosis in germ cells (sex) and mitosis in somatic cells. Meiosis has two divisions and mitosis has one division. Meiosis i separates homologous chromosomes and mitosis separates chromatids of chromosomes. Physical exchange of sequences between chromatids of homologous chromosome. When they form a tetrad, they"re not side by side, but rather on top of each other. Swapping pieces of one homologous chromosome to another. Protein complex ( synaptonemal complex") forms between homologous chromosomes. Segments of non-sister chromatids cross-over (forming chiasmata") are swapped. Results in new combinations of alleles on chromosomes. The letter case difference is for the difference in alleles. Another way to get gene combination is when they switch pieces but in the wrong place. We end up with two copies on one chromatid.