Biology 1201A Lecture Notes - Lecture 12: Stop Codon, Start Codon, Peptide
14 Mar 2016
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1. identify the sequence of standard start and stop codons 2. identify the function of start and stop codons. Is the first codon translated in any mrna in both prok and euk cells. Stop: (3 codons that do not specify aa"s): uaa, uag, uga (aka nonsense or termination codons). Indicate the end of a polypeptide encoding sentence. When a ribosome reaches a stop codon, polypeptide synthesis stops and the new polypeptide chain is released from the ribosome: compare the overall gene expression of prokaryotic vs. eukaryotic cells. (see last page) Post lecture: relative location of such dna sequence signals as promoter, 5" and 3" utr, sd box , start codon, stop codon, transcription terminator etc. Promoter: if the promoter is on the right then polymerase will bind on the right side and it will read 3-5" on the top strand.
