Biology 1201A Lecture Notes - Lecture 14: Leucine Zipper, Nuclear Membrane, Lac Repressor

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Reviewing sections relating to eukaryotic gene structure and function: 13. 4 and 14. 2, Post lecture outcomes: basic structure of eukaryotic vs prokaryotic cell with respect to gene expression. Eukaryotic cells have nuclear membrane that separate transcription and translation. This allows for sophisticated control and regulation that is not found in prokaryotes. Proks don"t have this so translation and transcription are coincident. Therefore proks don"t have any pre-mrna and pre- mrna can not be processed to do things like alternative splicing. Because translation and transcription happen at the same time, there is not a lot of transcriptional, translational and no post-transcriptional regulation. Side note: protein coding genes are also different in proks and euks. Both have promoter, start codon, stop codon and coding region. Eukaryotes have enhancers, promoter proximal region, exons and introns. Promoters have a terminator sequence while euaryotes have polyadenylation signal(poly a tails, and 5 cap).

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