Biology 1201A Lecture 17: Bio Lecture 17 March 9
12 Jan 2016
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Document Summary
Life requires the ability to catalyze reactions that lead, directly or indirectly to the production of more molecules like themselves. Rna has the unique potential to act as both information carrier and catalyst. Rna world is random function will depend on sequence = structure. Single stranded rna can fold into highly elaborate structures. Generate large pool of random dna transcribe. Rna molecules which have specific biochemical properties isolated speed not diversity of reactions. These properties include catalyzing a variety of reactions. Main difference between protein enzymes and ribozymes is reaction. Ribozyme with 2 functions structure determines function: ligase function, nuclease (dna cleavage) functions. An rna which can catalyze tempted polymerization would be important. If neighbouring rna have catalytic actions which are beneficial. A ribozyme, which can polymerize 100% of its length. Mutually beneficial rnas need to be close to a replicating ribozyme to benefit over time. In vitro experiments identify rna sequences which bind to amino acids.
