Biology 1002B Lecture Notes - Lecture 7: Howard Hughes Medical Institute, Dna Replication, Kinetochore

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Lecture 7: inheritance of sameness role of cytoskeleton in inheritance of sameness role of checkpoints. Dna polymerase cannot initiate dna synthesis, they can only elongate and continue the process that has already started. Involved in making sure the chromatids get into the daughter cells microtubules interact with dna actin filaments pinch off the cell. Checkpoints regulate the progression through the cell cycle cells will not divide, will not proceed into anaphase until all chromosomes are attached to spindle (metaphase checkpoint stop sign) Make sure all the chromosomes are properly partition. G1s checkpoint; cells won"t replicate their dna until it"s fully repaired. Checkpoint at the end of g2; check to see if chromosome is ready to condense and divide. A: bone marrow, gemeotic tissues, regenerating tissues, repairing injury, epidermis, during early development. A: root tips (meristem), shoots, trunk, growth of fruits.

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