Biology 1002B Lecture Notes - Lecture 4: Ribosomal Rna, Rhodopsin, Opsin

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blushporpoise372

10 Feb 2017

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Transcription translation mrna degradation / protein degradation. The rate of transcription & mrna degradation in uences how much protein is made. All quantities are measurable. (transcript abundance / protein abundance) Its degree of instability can be altered. Temporal regulation of gene expression. (rna decay is a good thing) Mrna breaks down more than rrna and rna because they have less folding. Genes that code for housekeeping proteins (necessary for cell survival) tend to have longer lived transcripts. Responses to a stress or stimulus are shorter lived. Half life: how long it takes for half of a speci c protein to degrade. 17 copies of mrna mrna < protein. Bacterial ribosomes are not the same size as eukaryotic. Run the rna blot the gel speci c probe detection of transcript. Chlamydomanas cells shifted from growth temperature of 24 c to 40 c. Highest abundance of hsp1 is at 40 c. Housekeeping proteins tend not to change abundances.

Related Questions

QUESTION 1

How is a bone marrow transplant able to treat someone with leukemia?

		The donor blood contains antibodies that destroy cancer cells
		Donor blood contains stem cells that regenerate cells in the immune system
		Bone marrow contains induced pluripotent stem cells that turn into red blood cells
		Bone marrow contains tumor supressor genes that slow down leukemia growth
		Bone marrow contains pluripotent human embryonic stem cells

1.2 points

QUESTION 2

What would happen if siRNAs designed to target mRNA from an oncogene were introduced into cancer cells?

		Increased genomic instability would result from adding foreign nucleic acids
		New mutations would arise in the oncogene
		The oncogene would be converted back into a proto-oncogene
		The siRNAs would compete with the oncogene's active site
		Production of the oncogene protein would decrease

1.2 points

QUESTION 3

What is the purpose of chromatin-remodeling enzymes in human cells?

		The enzymes control the rate of translation of an mRNA transcript
		The enzymes add phosphate or methyl groups to histone tails
		The enzymes slide nucleosomes farther apart or closer to each other
		The enzymes send damaged proteins to the proteasome for degradation
		The enzymes cause DNA looping to occur

1.2 points

QUESTION 4

If you wanted to resurrect the mammoth, how would you do it?

		Use somatic cell nuclear transfer to insert the mammoth genome into the egg of an elephant
		Use transcription factors to re-program adult cells from elephants into mammoth cells
		Change the gene expression patterns of elephants to increase production of mammoth genes
		Use siRNAs to decrease expression of elephant-specific genes in an elephant embryo

1.2 points

QUESTION 5

How is eukaryotic transcription initiated?

		RNA polymerase is recruited to the start codon by transcription factors
		RNA polymerase begins transcription at the enhancer sequence
		RNA polymerase is activated by binding to GTP
		An initiator tRNA binds to the ribosome
		A complex of proteins forms at the promoter of a gene

Biology 1002B Lecture Notes - Lecture 4: Ribosomal Rna, Rhodopsin, Opsin

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