Biology 1001A Lecture Notes - Lecture 9: Spindle Checkpoint, Wound Healing, Intermediate Filament

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Focus on cytoskeleton separation during mitosis mitosis program. Checkpoint during middle of mitosis the spindle assembly checkpoint/ mitotic spindle checkpoint chromosomes cannot proceed into anaphase until all of the chromosomes are attached to spindle fibres. Another mechanism that insures inheritance of sameness. G2 checkpoint make sure the cell/chromosomes are ready to enter mitosis. Blood, stem cells, tissue to repair, skin cells, gametes, when they grow anywhere that cells need to be reproduced. In the roots and shoots, branches, meristem tissue, under the bark in the trunk, growth, wound repair. How much human variation is there: venter individual genome sequence showed 1. 2 million variants, of variant bases are snps; Bacterial elements code for their own mobility (transposase) Central sequence codes for a gene called transposase which makes cuts in the backbone of a target sequence which initiates the movement of these elements. If two is elements are nearby, they can move everything in between them.

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