Biology 1001A Lecture 5: Cycle 5 (Bio 1001A)

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Characteristics of mendel"s work that set him apart as a genetic researcher. Mendel"s most important innovation was his quantitative approach to science, specifically his rigour and statistical analysis. Mendel studied heritable characteristics called racters in pea-plants. Laid the foundations for genetics- came up with fundamental models of inheritance using controlled crosses and quantitative analysis ; Knew nothing about mutation, meiosis, cells or nuclei. Introduced new terms such as characters and traits. Principle of segregation: the pair of alleles separate/ segregate when gametes form. Principle of independent assortment: alleles for two different genes segregate. Components of mendel"s explanatory model independently of each other. Variation in traits is due to different alleles. Organisms inherit two alleles for each trait; genes are present in two copies. Appearance of heterozygotes determined by dominant alleles. Distribution of progeny (offspring), given parental genotypes in monohybrid and sex-linked crosses. Cross between two heterozygotes is called a monohybrid cross with 2 traits only (aa x.

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