Biology 1001A Lecture Notes - Lecture 5: Dna Replication, Telomerase, Telomere
17 Dec 2017
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Diploid after replication so its 4c not 2c. Semi-conservative: composed of one new and one old strand. Dna chains grow by extending the 3" end, all polymerases can only extend a 3" end of template. Dna happens because of replisomes (whole complex) replicate one continuously and one discontinuously (semi-discontinuous) built at replication fork. Fork on either side of bubble 2 forks/2 replisomes traveling in opposite directions. Last bubble on end of chromosome- polymerase i removes the last rna primer and no. 3" oh to grow more dna o o. Every replication chromosomes get smaller and this is important because you know how old your cells are. When you make gametes you need to elongate telomeres to give to baby. Telomerase brings own rna template to know which dna to add , telomere is making dna from rna template to be able to put on a primer so polymerase iii can extend primer .
