Biology 1001A Lecture Notes - Lecture 8: Gene Pool, Epistasis, Cyclic Adenosine Monophosphate
21 Nov 2016
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*cycle 1 pointed out that evolution is dependent upon the inheritance of genetic variability. *cycle 2 was mainly concerned with the various mechanisms that try to ensure that accurately replicated genetic information gets inherited by daughter cells. The dna polymerase reverses and removes the most recently added base if it is mispaired as a result of a replication error. The enzyme then resumes dna synthesis in the forward direction. Enzymes recognize distorted regions caused by mispaired base pairs and remove a section of dna that includes the mispaired base from the newly synthesized nucleotide chain. A dna polymerase then resynthesizes the section correctly, using the original template chain as a guide. The two major types of bacterial tes: Insertion sequences (iss): the simplest tes they are relatively small and contain only genes for their transposition, notably the gene for transposase. Transposons: has an inverted repeat sequence at each end enclosing a central region with one or more genes.
