Biology 3338A Lecture Notes - Lecture 1: Ian Wilmut, Camera Dolly, Xenopus
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1. | In addition to identifying the genetic material, the experiments of Avery, MacLeod, and McCarty with different strains of Streptococcus pneumoniae demonstrated that | ||||||||||
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2. | In order to show that DNA in cell extracts is responsible for genetic transformation in Streptococcus pneumoniae, important corroborating evidence should indicate that _______ also destroy transforming activity. | ||||||||||
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3. | Based on what you have learned about the experiments conducted by Griffith and Avery and colleagues with bacteria, which of the following would result in transformation of living R cells? | ||||||||||
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4. | A-T base pairs in a DNA double helix | ||||||||||
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5. | If 23 percent of the bases in a sample of double-stranded DNA are adenine, what percentage of the bases are uracil? | ||||||||||
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6. | The uniform diameter of the DNA structure provides evidence for | ||||||||||
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7. | If a sequence of one strand of DNA is 5â²-TGACTATC-3â², what is the complementary strand? | ||||||||||
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8. | What structural aspect of the DNA facilitates dissociation of the two DNA strands for replication? | ||||||||||
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9. | If the MeselsonâStahl density gradient experiment had resulted in two bands of DNA molecules after only one round of replication, one containing only 15N and the second only 14N, this result would have indicated that replication was | ||||||||||
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10. | The nucleoside analogue acyclovir, which is used to treat herpes simplex virus (HSV) infections, lacks a 3â² hydroxyl group (âOH). Predict what will happen if the host cell DNA polymerase incorporates a molecule of acyclovir into an elongating strand of HSV DNA. | ||||||||||
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11. | Which of the following does not demonstrate the stability of the DNA double helix? | ||||||||||
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12. | What effect would a primase inhibitor have on DNA replication? | ||||||||||
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13. | To replicate their DNA in a timely manner, most eukaryotic chromosomes | ||||||||||
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14. | Which statement about DNA replication is false? | ||||||||||
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15. | In many eukaryotes, there are repetitive sequences called telomeres at the ends of chromosomes. After successive rounds of DNA replication, the _______ strand becomes shorter. In some cells, an enzyme called _______ repairs the shortened strand. | ||||||||||
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16. | A researcher studies normal human fibroblast cells. They can be maintained in culture but die off after about 30 cell generations. Unexpectedly, a colony of cells continues to survive and divide past 30 generations. Which scenario is most likely true for these cells? | ||||||||||
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17. | If DNA polymerase III introduces an incorrect nucleotide, what is the first corrective action made by the DNA repair system? | ||||||||||
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18. | Choose the correct order of the following four events in the excision repair of DNA: (1) Base-paired DNA is made complementary to the template. (2) Damaged bases are recognized. (3) DNA ligase seals the new strand to existing DNA. (4) Part of a single strand is excised. | ||||||||||
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19. | Six complete cycles of PCR should result in a _______-fold increase in the amount of DNA. | ||||||||||
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20. | When double-stranded DNA is heated to temperatures above 90°C, it denatures. Denaturation is a process that | ||||||||||
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Question 9
Codominance is a form of inheritance in which two different allelesfor a gene are both expressed, and neither allele is dominant overthe other. One example of codominance is fur color in cattle; thealleles for red fur and white fur are codominant. If a homozygousred cow and a homozygous white bull mate, what would you expect tofind in their offspring?.912.l.16.2>
They will all have white fur.
Their fur will be a mixture of red and white hairs.
Their fur will be a lighter shade of red.
They will all have red fur.
Question 10
If a tRNA molecule has an anticodon which reads AUG, what will itmatch up with and what amino acid is it carrying?
.912.l.16.5>
U | C | A | G | ||||||
UUU | Phenylalanine | UCU | Serine | UAU | Tyrosine | UGU | Cysteine | U | |
U | UUC | Phenylalanine | UCC | Serine | UAC | Tyrosine | UGC | Cysteine | C |
UUA | Leucine | UCA | Serine | UAA | Stop | UGA | Stop | A | |
UUG | Leucine | UCG | Serine | UAG | Stop | UGG | Tryptophan | G | |
CUU | Leucine | CCU | Proline | CAU | Hisitidine | CGU | Arginine | U | |
C | CUC | Leucine | CCC | Proline | CAC | Hisitidine | CGC | Arginine | C |
CUA | Leucine | CCA | Proline | CAA | Glutamine | CGA | Arginine | A | |
CUG | Leucine | CCG | Proline | CAG | Glutamine | CGG | Arginine | G | |
AUU | Isoleucine | ACU | Threonine | AAU | Asparagine | AGU | Serine | U | |
A | AUC | Isoleucine | ACC | Threonine | AAC | Asparagine | AGC | Serine | C |
AUA | Isoleucine | ACA | Threonine | AAA | Lysine | AGA | Arginine | A | |
AUG | Methionine/Start | ACG | Threonine | AAG | Lysine | AGG | Arginine | G | |
GUU | Valine | GCU | Alanine | GAU | Aspartate | GGU | Glycine | U | |
G | GUC | Valine | GCC | Alanine | GAC | Aspartate | GGC | Glycine | C |
GUA | Valine | GCA | Alanine | GAA | Glutamate | GGA | Glycine | A | |
GUG | Valine | GCG | Alanine | GAG | Glutamate | GGG | Glycine | G |
It is carrying arginine and will match with a CGU codon on themRNA.
It is carrying methionine and will match with a TAC codon on theDNA.
It is carrying methionine and will match with a UAC codon on themRNA.
It is carrying tyrosine and will match with a UAC codon on themRNA.
Question 11
While the DNA in a human skin cell was being replicated, a singlebase was miscopied. What will be the most likely result of this forthe cell in which it happened?.912.l.16.3>
All the proteins the cell creates from the miscopied strand willdo different jobs than the old ones.
If the new sequence codes for the same amino acid as theoriginal cell, it will function normally.
Both new DNA strands will end up together in a new cell, and theinaccurate one will be discarded.
Any miscopied DNA will be replaced with an accurate DNA copyonce the cell divides.
Question 12
A ferret's haploid number of chromosomes is 20. How would thenumber of chromosomes in the ferret's body cells compare to thenumber of chromosomes in its gametes?.912.l.16.17>
Its body cells would have 20 chromosomes, and its gametes wouldhave 40 chromosomes.
Its body cells and gametes would both have 40 chromosomes.
Its body cells and gametes would both have 20 chromosomes.
Its body cells would have 40 chromosomes, and its gametes wouldhave 20 chromosomes.
Question 13
A body cell is in the longest stage of its life cycle. The cellgrows, synthesizing proteins and increasing in size. Eventually,the cell will grow too large to carry out normal activities. Whichof the following is the best conclusion you can make about the lifecycle of this cell?.912.l.16.14>
The cell is close to the end of its life cycle, and a chemicalsignal will initiate cell death.
The cell is ready to undergo mitosis, and a chemical signal willsend the cell to prophase.
The cell is in the G1 phase of interphase, and a chemical signalwill send the cell to the S phase.
The cell is in the S phase of interphase, and a chemical signalwill move the cell to the G2 phase.
Question 14
While mRNA strands are being created a sequence is sometimesmiscopied. What is the best possible outcome for the cell shouldthis take place?.912.l.16.5>
The miscopied sequence codes for the same amino acids as theoriginal sequence.
The new sequence creates a protein that serves a differentfunction from the original.
The ribosomes will correct the mistake before the tRNA matchesan amino acid to it.
The mRNA will only be used to create non-critical proteins forthe cell.
Question 15
Over the last several decades, the scientific community hasgathered a large amount of information regarding genetics andgenetic variation. What are two main sources that lead toincreased genetic variation?.912.l.15.15>
Selective breeding
Gamete mutations
Recombination
Genetic drift