Biochemistry 2280A Lecture Notes - Lecture 2: Scoville Scale, Capsaicin, Amine
13 Sep 2016
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Capsaicin measured in scoville units, hydrophobic and interacts with pain receptors. Amino acids (you need to memorize all 20 amino acids, codes, etc. Non polar side chains: hydrophobic, hydrogens on these chains can be lost as protons which would render a negative charge, exceptions: proline is an imino acid and is cyclic. Polar, charged side chains: negative charge at neutral ph. Acidic side chains: side chains lose their protons and then have a negative charge. Physical size (generally just know whether a n amino acid is big or small: no particular trend in terms of size. We classify whether an amino acid is charged or not at neutral ph: The ph scale: an index of the concentration of protons, a ph of 7 is 1x10-7 m of protons, goes by tenfolds. By calculating the ph: calculate the extent of ionization of a group, from this, calculate the net charge on this group.
