PSL301H1 Lecture Notes - Lecture 18: Altitude Sickness, Red Blood Cell, Pulmonary Hypertension

• School: UTSG
• Department: Physiology
• Course: PSL301H1
• Professor: French, Gramolini, Richardson, Wong

Document Summary

Lecture 6: respiratory system high altitude and exercise. 253 x 0. 21 = 53 mmhg: barometric pressure at summit of mt. Everest: 253 mmhg (normal sea level is 760 mmhg) Everest you are experiencing lower than normal levels of oxygen in the air: you need more o2 causes an increase in arterial co2 (metabolizing different things, arterial o2 is dropping because atmospheric. Co2 + h2o h2co3 h+ + hco3- It"s going to decrease because you"re blowing off the co2 in your lungs: going to the left side of the equation now from hco3. In the short term chemoreceptors activated, increase ventilation and increase respiratory rate, tidal lower, unloading oxygen is unlikely to be different even if ph of blood has gone up volume. Longer-term physiological response for adaptation to higher altitude: release of erythropoietin stimulates red blood cell production (due to low po2 levels at the.