PSL301H1 Lecture Notes - Lecture 23: Ascending Limb Of Loop Of Henle, Plasma Osmolality, Vascular Organ Of Lamina Terminalis

• School: UTSG
• Department: Physiology
• Course: PSL301H1
• Professor: French, Gramolini, Richardson, Wong

Document Summary

The amount of insensible water loss is variable. In every body, under all conditions, you lose a lot of water every day through. Breath breathe in dry air, it equilibrates and gets hydrated. Urine value does not equal water intake, negligible feces water loss. Through changes in serum sodium concentration (osmolality) detected by the: water balance how is it regulated? osmoreceptor in the hypothalamus (swelling or shrinking) Increased thirst and water drinking (osmoreceptor) exercising, sends 2 signals out to increase adh and to replace water deficit. There is a pathway from the arteriole stress receptor and adh synthesis and secretion: aspect of cardiac output has effects on adh secretion, baroreceptors in the carotid sinus. The hypothalamic osmoreceptor: located in the anterior hypothalamus. Cell swells with hypernatrium, and shrinks with hyponatremia. When osmoreceptor cells shrink, channels open, cations enter and depolarize cell: leading to action potentials which lead to increased.