PCL201H1 Lecture Notes - Lecture 1: Ebers Papyrus, Paroxetine, Atorvastatin

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Lecture 1 introduction to pharmacology: what is pharmacology, a brief history of pharmacology, importance of pharmacology, aspects of pharmacology. The science of drugs, the study of action and fate in the body. Pharmacy: health profession concerned with preparing, dispensing, and safely and effectively using medication. Therapeutics: the treatment of disease (using drugs or other means) Toxicology: a science focusing on chemicals with undesirable biological activity. Pharmacology is a basic and clinical biomedical science: understanding the interaction between drugs and drug targets, gain insight into normal and abnormal function, and thereby improving therapeutics, a brief history of pharmacology. Ancient civilizations: various natural sources have been used, china: pen ts"ao (great herbal, 2735 bc) 40 volumes of medicinal and toxic plants, antidotes: egypt: ebers papyrus (1500 bc) Greece and roman empire: hippocratic corpus (5th century bc- 2nd century ad) Rejected divine/spiritual causes and treatment of disease.

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