PCL102H1 Lecture Notes - Lecture 2: Hippocratic Oath, Cardiac Glycoside, Polypharmacy

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Correct disease deficiencies with herbs of similar qualities. Opposites cure opposites cure by giving herbs with properties opposite to the humoral imbalance. The body will take from the mixture whatever will correct the humoral imbalance. More to learn outside universities than inside them. Taverns are the ideal venue acquire knowledge folk remedies. Believed in three elements mercury (volatility) sulfur (combustibility) salt (cohesiveness) Introduced new chemical remedies chemicals that wouldn"t have been used under the humoral system. Wanted to find essence of herbs and minerals (as they existed at creation of the universe) monotherapy single herbs and minerals any therapeutic benefit can be attributed to a single drug. Chemical advances distillation separate compounds in mixture based on property of volatility concentration evaporation. Modern medicine derived from natural sources: digitalis (from purple foxglove) Cardiac glycosides (digitoxin and digoxin) found in digitalis. Used to treat cardiac arrhythmias and heart failure: morphine (from opium poppy) Historically used to treat fever, headache, and pain.

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