NFS284H1 Lecture Notes - Lecture 14: Healthy Choice, Leptin, Chyme
20 Feb 2015
School
Department
Course
Professor
Document Summary
Hormone secreted by the stomach, stimulates eating at set times. Levels in the blood rise before a meal, stimulating hunger. Levels in blood decline after a meal, reducing hunger. Released when chyme enters the small intestine, suppresses food intake. Other food intake suppressing hormones: peptide pyy, glp-1 (which also stimulates the release of insulin) In obese individuals ghrelin levels do not decline as much as in lean individuals after the start of a meal; this may result in prolonged eating in a meal. Glp-1 levels tend to be lower in obese than lean individuals, this may increase the length of a meal. Drugs that mimic glp-1 or prevent its degradation are used in the treatment of both type-2 diabetes and obesity. Change in ghrelin levels in the blood is more important than the initial level. Leptin: hormone secreted into the blood by adipose tissue. Directly proportional to the amount of adipose tissue.
