KPE161H1 Lecture Notes - Lecture 11: Membrane Transport Protein, Membrane Transport, Glucagon

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Involved in signaling telling another cell what to do: two methods for signaling (1) nerves (2) hormones slower process. Types of hormones: three types, (1) steroid-derived hormones. Based on cholesterol (a type of fat: (2) polypeptide or amine hormones (from amino-acids) Bits of smaller proteins: (3) prostaglandins biologically active lipids, vary according to function and solubility, solubility is important tells us where hormone can or cannot travel to, can be water (blood soluble) or lipid soluble. If lipid (fat) soluble travel easily into cells through membrane since membranes are lipid based: but not transported well in the blood, have to be attached to carrier protein, receptors inside cell. Water (blood) soluble can"t pass into cells: receptors on surface of cell, receptor is a lock, hormone is a key. Receptors for thyroxine (from thyroid) regulate cellular metabolism. In almost all cells of body overall metabolism. Kpe161: or may be in specific cell.

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