HMB440H1 Lecture Notes - Lecture 5: Vascular Dementia, Neocortex, Astrocyte
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Lecture 5: dementia - a symptom, not a. Cognitive symptoms that interfere with your usual work and it is not explained by delirium/psychiatric disorder and there is a detectable change (not just in memory) o. Could be personality/behavioral changes, motor disturbances, and cognitive symptoms. Dementia is an umbrella term to describe various diseases that cause impairment in thinking/memory skills (e. g. ad, New dementia criteria to characterize the 3 major non-amnestic variants of ad is the presence of non-amnestic presentations: o o o logopenic variant primary progressive aphasia (ppa) = language impairments posterior cortical atrophy variant = visual processing problems. Younger onset of ad (yoad) is more likley to present with non-amnestic symptoms o. Yoad patients have greater gray matter (gm) atrophy and more abundant senile plaques, nft, and synaptic loss o. Yoad also more likley to present with language impairment, attention/executive function, and visuospatial function.
