CSB346H1 Lecture Notes - Lecture 4: Sickle-Cell Disease, Blood Plasma, Action Potential

• School: UTSG
• Department: Cell and Systems Biology
• Course: CSB346H1
• Professor: David Lovejoy

Document Summary

Lecture 1 introduction to the respiratory control system. Immune cell first line of defense, eat up all the crappy stuff you inhaled. Epithelial type i cell where diffusion occurs b/c v. thin membrane. Type ii produces surfactant reduces surface tension to keep the space inflated. Medullary respiratory neurons send action potentials when you breathe in and out where breathing is generated: they are the command centre that tells motor neurons (muscle cells) when to contract. Functions of the respiratory system: pulmonary ventilation ventilating the lungs, gas & transport exchange getting o2 and co2 from lung into the blood, acid-base balance (ex. Hco3: speaking and vocalization, immune protection, regulation of body temperature (ex. dogs panting) Capillary wraps around the alveoli to increase sa to get o2 and create lots of opportunities. 2 features that are optimized to diffuse oxygen: super thin membrane. Increase exposure and sa to capillaries in alveolar space.