BCH210H1 Lecture Notes - Lecture 17: Facilitated Diffusion, Cyclic Adenosine Monophosphate, Glycogen

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Stavroula Andreopoulos

Document Summary

For bacteriorhopsin you should know the key residues, and know the order of events. Understad the role of retinal which is a sensor for light. Facilitated transport is where the proteins help move the molecule across the membrane. The molecules are always going down the concentration gradient. These proteins can discriminate what goes through the bilayer. As we increase the substrate conc of water, we get a linear relationship, it keeps going. With facilitated diffusion, we see a hyperbolic curve and it eventually plateous. Ea(cid:272)h (cid:272)olour represe(cid:374)ts a (cid:373)o(cid:374)o(cid:373)er, it"s a tetra(cid:373)er spe(cid:272)ies. Theres a hole i(cid:374) the (cid:272)e(cid:374)ter of the (cid:272)ha(cid:374)(cid:374)el. Each of the 4 subunits contributes a 5 aa reentrant loop which is not helical. Instead of pointing its side chains into the selectivity filter, its points its backbone into th selectivity filter. The backbone is doing the filtering, not the side chains. This very narrow filter forces an ion to give up water.