BCH210H1 Lecture 29: Electron Transport (Nov. 17, 2017)
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BCH210H1 Full Course Notes
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Electron transfer potential: electron transfer chain and molecules, ecc and atp synthase inhibitors, discovery of oxidative phosphorylation. Metabolism and bioenergetics has 12 lectures in total. Examine how electrons flow through the electron transport chain in order to generate a proton gradient using e o --> to drive atp synthesis. Recognize the relationship and importance between the proton motive force and atp synthesis. Describe an experimental approach to study oxidative phosphorylation. Below is the inside of the mitochondria and inside, we have the matrix. This is where these reactions will be taking place --> conversion of pyruvate and kreb cycle: recall 7/8 kreb cycle enzymes are soluble while sdh is complex ii in the electron complex chain. This sdh will transfer fadh2 into the ecc. Nadh and fadh2 will be donating its electrons into the chain below. Complex i: nadh-q oxidoreductase --> passes electrons to coenzyme q: pumps 4 protons across intramitochondrial membrane.
