ANA300Y1 Lecture Notes - Lecture 21: Cell Adhesion Molecule, Clonal Deletion, Passive Immunity
Document Summary
Few antigen-reactive t-cells result in a much larger population of antigen-reactive t-cells (also termed clonal expansion ); end result of t-cell activation depends on specific type of t-cell activated; most. T-cells can be categorized as either cd4+ or cd8+ cells: cd4 is expressed on approximately 60% of mature t-cells; Fc is the nonvariable base" of the antibody molecule: other triggers of mast cell degranulation include c5a and. When antigen enters body, it"s first processed by antigen-presenting cells, then presented to lymphocytes, the major effector cells of the immune system this causes the lymphocytes (t and b cells) to proliferate and transform: *cells, particularly lymphocytes, are the (cid:498)key players(cid:499) in the immune response: is due to the transformation of b cells into antibody-producing plasma cells (antibodies are also termed immunoglobulins) Humoral immunity is a function of b cells. Antigen/antibody and antigen/ complement capture in lymphoid tissues. Proliferation into plasma cells and memory cells. Production and secretion of antigen-specific immunoglobulin (antibodies)
