PSYB65H3 Lecture Notes - Lecture 3: Synaptic Pruning, Radial Glial Cell, Neuroglia
Document Summary
Epigenetics; if a portion of dna becomes methylated (attaching methyl groups) then transcription cannot take place. Neurotrophic factors; chemical that supports growth and differentiation in developing neurons. Neurogenesis occurs just after 5 weeks after birth. They then form a map by migrating to different areas. Body and brain weight both increase accordingly during development. Neural differentiation begins after 7 weeks and largely complete by 5 months. Best time to have injury to neuron is after 5 weeks because neurogenesis has just begun and fetus can adapt to the injury. Continues for 6 weeks in cortex and longer in hippocampus. Radial glial cells act as a path for the neurons to follow to their home Dendritic growth; dendrites begin to grow and seek other neurons. Slower growth than axons, but much higher in numbers. Axonal growth; axons of neurons extend to certain lengths and form synapses formation.
