NROC61H3 Lecture Notes - Lecture 6: Dopamine Antagonist, Reward System
Document Summary
The location where they received the stimulation was rewarding: rat turns the wheel to receive the electrical stimulation. Increase in rates of self stimulation at low stimulation frequencies: dopamine antagonist you need to response more to achieve the same amount of reward with icss. Dopamine is mediated by the na in icss: as you lower the dose of amp, they are increases the amount of lever press they are making. Therefore the lower the dose the increased response. Lower dose of icss they lever press less. There consumption of food goes up and average weight goes up as well: they are running faster to get to the reward because they have enhanced wanting.
